JACKSONVILLE – The Jaguars could be thin at receiver Sunday.
They also will be making game-day decisions on the defensive interior.
Rookie wide receiver DJ Chark Jr., who has played his way into the Jaguars' top three receivers in recent weeks, will miss Sunday's game against the Buffalo Bills – and defensive tackles Marcell Dareus and Eli Ankou both will enter the weekend as questionable.
Chark, who has 10 receptions for 87 yards in the last four games, will miss Sunday with a quadriceps injury. Chark, one of the team's top gunners on punt coverage, had played in all 10 games this season.
"It's always disappointing when a guy is really starting to come on (and can't play because of an injury)," Jaguars Head Coach Doug Marrone said of Chark. "He's doing really well special-teams-wise; everyone saw that. But he's doing really well in practice offensively.
"It's a shame, especially when you're young; you don't want any type of setbacks during the season. But it seems like that's what's been going on."
Chark's injury leaves the Jaguars with four healthy receivers on the active roster: Donte Moncrief, Dede Westbrook, Keelan Cole and Rashad Greene Sr. The team also has rookie Allen Lazard on the practice squad.
Westbrook leads the Jaguars' wide receivers this season with 40 receptions for 484 yards and three touchdowns, with Moncrief adding 33 receptions for 488 yards and three touchdowns.
Chark has 14 receptions for 174 yards and Cole has 29 receptions for 375 yards and a touchdown. Greene has three receptions for 28 yards.
Dareus, a starter in all 10 games this season, is listed as questionable after not being listed as practicing Wednesday and Thursday and practicing limited on Friday. Nose tackle Eli Ankou is listed as questionable after being listed as limited the last three days with a calf injury.
Starting guard A.J. Cann (hamstring) also was listed as questionable. He started in a loss to the Pittsburgh Steelers last Sunday after being listed as questionable entering the weekend but left after reaggravating the injury.
The Jaguars on Friday also ruled out the following players for Sunday: cornerback Quenton Meeks (knee), linebacker Lerentee McCray (hamstring) and offensive lineman Josh Walker (foot/ankle).
Cornerback Jalen Ramsey (groin) and right tackle Jermey Parnell (knee) were removed from the game status report Friday and therefore are expected to play Sunday.
Also Friday, left tackle Josh Wells returned to practice. He currently is on injured reserve and would be eligible to return to the active roster for the team's final three games. Marrone said Wells looked good in practice Friday.
Wells started Weeks 3-5 before sustaining a groin injury in a Week 5 loss to Kansas City. He has been on injured reserve since.
The Jaguars will visit the Bills at New Era Field in Orchard Park, New York, Sunday at 1 p.m.